HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-bromo-4H-thieno(3,2-b)pyrrole-5-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | ethyl 2-bromo-4H-thieno[3,2-b]pyrrole-5-carboxylate | HCID 13164349 | — |
| Product | 2-bromo-4H-thieno(3,2-b)pyrrole-5-carboxylic acid | HCID 22556490 | — |
Reaction Steps
2-Bromo-4H-thieno[3,2-b]pyrrole-5-carboxylic acid ethyl ester (Eras, J.; Galvez, C.; Garcia, F., J. Heterocycl. Chem., 21: 215-217 (1984)) was hydrolyzed according to Procedure D (after cooling to room temperature, acidification with 2 N HCl; resultant precipitate filtered, suspended in toluene, concentrated; no purification).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06576653B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-fbda73132a89485eb889b72ab2d59aa3 |
| Source note | uspto-grants-2003_06 |