Lithium hydroxide, monohydrate → HCID 15657633, compound

HRID 1369001Notes

Reaction equation

HRID 1369001 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH2:8][CH:9]=[C:10]2[C:13]([O:15]C)=[O:14])=[CH:5][CH:4]=1.O[Li].O>>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH2:8][CH:9]=[C:10]2[C:13]([OH:15])=[O:14])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 23567163HCID 23567163, compound

Product 1

HCID 15657633HCID 15657633, compound

Procedure

The sub-title compound was prepared according to the method described in Example 1(ii) above from 7-methoxy-3,4-dihydronaphthalen-1-yl-carboxylic acid, methyl ester (0.39 g; 1.79 mmol; from step (i) above) and LiOH.H2O (0.15 g; 3.57 mmol). Yield 148 mg (40%).

Sources & evidence

ORD record
ord-13963a78466949bcad98540cbf8bf855
Source dataset
uspto-grants-2003_06
Patent number
US06576657B2

Reaction notes

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