HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-1,4-dichlorobenzene → 1-(2-Diethylaminoethyl)-4-trifluoromethyl-6-iodo-3-hydroxy-3-(2,5-dichlorophenyl)oxindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-1,4-dichlorobenzene | HCID 15033 | — |
| Reactant | 1-(2-Diethylaminoethyl)-4-trifluoromethyl-6-iodoisatin | HCID 11026552 | — |
| Product | 1-(2-Diethylaminoethyl)-4-trifluoromethyl-6-iodo-3-hydroxy-3-(2,5-dichlorophenyl)oxindole | HCID 18518572 | 51% |
Reaction Steps
The title compound (137 mg, 51%) was prepared from 1-(2-diethylaminoethyl)-4-trifluoromethyl-6-iodoisatin (200 mg, 0.454 mmol) and 2,5-dichlorobromobenzene by the procedure similar to that described Example 92(1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06576656B1 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-b198b6049c38420b97ca8dfe3c565b49 |
| Source note | uspto-grants-2003_06 |