HCID 12071478, compound → HCID 18518262, compound

Participants

Reaction Steps

According to the procedure of Example 6 (c), except substituting ethyl (±)-10,11-dihydro-3-[3-[4-(ethylthio)pyridin-2-y lamino]-1-propyloxy]-5H-dibenzo[a,d]cycloheptene-10-acetate for the ethyl (R)-10,11-dihydro-3-[3-(pyridin-2-ylamino)-1-propyloxy]-5H-dibenzo[a,d]cycloheptene-10-acetate, the title compound was prepared as a yellow: 1H NMR (400 MHz, DMSO-d6) δ7.77-7.76 (d, 1 H), 7.17-7.15 (d, 1 H), 7.13-7.12 (d, 2 H), 7.08-7.07 (m, 1 H), 6.96-6.94(d, 1 H), 6.81-6.80 (s, 1 H), 6.68-6.67 (d, 1 H), 6.52 (s, 1 H), 6.35-6.33 (d, 2 H), 6.30 (s, 1 H), 4.20-4.16 (d, 1 H), 3.99-3.96 (t, 2 H),3.89-3.85 (d, 1 H), 3.65-3.63 (m, 1 H), 3.36-3.32 (m, 2 H), 3.22-3.15 (m, 1 H), 2.96-2.90 (m, 2 H); 2.85-2.78 (m, 1 H), 2.62-2.56(m, 2 H), 1.94-1.90(m, 2 H), 1.26-1.22 (t, 3 H), MS (ES) m/e463.4(M+H)+.

Provenance & Evidence