HCID 12071478, compound → HCID 18518253, compound

Participants

Reaction Steps

According to the procedure of Example 6 (c), except substituting ethyl (±)-10,11-dihydro-2-methyl-3-[3-(pyridin-2-ylamino)-1-propyloxy]-5H-dibenzo[a,d]cycloheptene-10-acetate for the ethyl (R)-10,11-dihydro-3-[3-(pyridin-2-ylamino)-1-propyloxy]-5H-dibenzo[a,d]cycloheptene-10-acetate, the title compound was obtained as an off white solid. 1H NMR (400 MHz, CDCl3) δ7.75 (d, 1 H), 7.65 (t, 1 H), 7.15 (m, 3 H), 7.05 (m, 1 H), 6.83 (s, 1 H), 6.7 (d, 1 H), 6.65 (m, 1 H), 6.60 (s,1 H), 4.25 (d, J=15.1 Hz, 1 H), 4.05 (t, 2 H), 3.80 (m, 1 H), 3.75 (d, J=15.1 Hz, 1 H), 3.50 (t, 2 H), 3.25 (dd, 1 H), 2.85 (dd, 1 H), 2.68 (dd, 1 H), 2.60 (dd, 1 H), 2.15 (t, 2 H), 2.10 (s, 3 H); MS (ES) m/e 417.3 (M+H)+.

Provenance & Evidence