反应详情

A mixture of 20 g (80 mmol) of 2,4-dihydroxy-4′-chlorobenzophenone, 21.9 g (88 mmol) of 1-bromododecane and 8.4 g (100 mmol) of sodium hydrogen carbonate is heated in 77.6 g of sec-butanol and 25.6 g of water and refluxed for 20 hours. The reaction mixture is then stirred for 15 minutes in the presence of 0.8 g of active carbon and filtered while warm. The product crystallizes upon cooling. After recrystallization from sec-butanol, 21.5 g of pale yellow crystals are obtained having a melting point of 61-63° C.

1. filtrationfiltered
2. temperaturewhile warm
3. customThe product crystallizes
4. temperatureupon cooling
5. customAfter recrystallization from sec-butanol, 21.5 g of pale yellow crystals
6. customare obtained