Tetrahydrofuran → Methyl 2-(4-{[(3,4-dichloro-5-cyano-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)-1,3-thiazole-5-carboxylate
Reaction equation
[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[Cl:17][c:18]1[c:19]([C:26](=[O:27])[Cl:28])[nH:20][c:21]([C:24]#[N:25])[c:22]1[Cl:23].[NH2:1][CH:2]1[CH2:3][CH2:4][N:5]([c:8]2[s:9][c:10]([C:13](=[O:14])[O:15][CH3:16])[cH:11][n:12]2)[CH2:6][CH2:7]1>>[NH:1]([CH:2]1[CH2:3][CH2:4][N:5]([c:8]2[s:9][c:10]([C:13](=[O:14])[O:15][CH3:16])[cH:11][n:12]2)[CH2:6][CH2:7]1)[C:26]([c:19]1[c:18]([Cl:17])[c:22]([Cl:23])[c:21]([C:24]#[N:25])[nH:20]1)=[O:27]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-b952fec30c724fd1afb74f266597c41d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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