Ethanol → HCID 69752797, compound

HRID 1369578Notes

Reaction equation

HRID 1369578 reaction equation
CC1[CH:7]=[CH:6][CH:5]=[C:4](C)[C:3]=1[CH:9]=[CH:10][C:11]1[C:12]2[N:13]([C:17]([CH3:21])=[C:18]([CH3:20])[N:19]=2)[CH:14]=[CH:15][CH:16]=1.[CH2:22]([OH:24])[CH3:23].[H][H].[CH3:27]O>[Pd]>[CH3:27][C:9]1[CH:3]=[C:4]([O:24][CH2:22][CH3:23])[CH:5]=[C:6]([CH3:7])[C:10]=1[C:11]1[C:12]2[N:13]([C:17]([CH3:21])=[C:18]([CH3:20])[N:19]=2)[CH:14]=[CH:15][CH:16]=1

Participants

6

Reactant 4

HCID 702EthanolHCID 887MethanolHCID 69750316HCID 69750316, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 69752797HCID 69752797, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

8-(2-(2,6-dimethylphenyl)ethenyl)-2,3-dimethylimidazo[1,2-a]pyridine was solved in methanol (3 ml) and ethanol (2 ml) and Pd/C (10%) (40 mg) was added. The mixture was hydrogenated at room temperature and atmospheric pressure until the uptake of hydrogen ceased. Following filtration through celite, the solvents were evaporated under reduced pressure to give the title compound, (0.069 g, 100%).

Workup

  1. customwas hydrogenated at room temperature
  2. filtrationfiltration through celite
  3. customthe solvents were evaporated under reduced pressure

Sources & evidence

ORD record
ord-a51584eaff8143cb98b9bd83724d369d
Source dataset
uspto-grants-2003_06
Patent number
US06579884B1

Reaction notes

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