Dichloromethane → 4-(4-chloro-1-methylpyrazol-5-yl)-N-[1-(3,4-difluorophenyl)-3-(1,3-dioxoisoindol-2-yl)propan-2-yl]-5-methylfuran-2-carboxamide
Reaction equation
[Br:56][P+:57]([N:58]1[CH2:59][CH2:60][CH2:61][CH2:62]1)([N:63]1[CH2:64][CH2:65][CH2:66][CH2:67]1)[N:68]1[CH2:69][CH2:70][CH2:71][CH2:72]1.[CH:40]([N:41]([CH2:42][CH3:43])[CH:44]([CH3:45])[CH3:46])([CH3:47])[CH3:48].[Cl:1][c:2]1[cH:3][n:4][n:5]([CH3:16])[c:6]1-[c:7]1[cH:8][c:9]([C:13](=[O:14])[OH:15])[o:10][c:11]1[CH3:12].[Cl:73][CH2:74][Cl:75].[NH2:17][CH:18]([CH2:19][N:20]1[C:21](=[O:30])[c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]2[C:28]1=[O:29])[CH2:31][c:32]1[cH:33][c:34]([F:39])[c:35]([F:38])[cH:36][cH:37]1.[P-:49]([F:50])([F:51])([F:52])([F:53])([F:54])[F:55]>>[Cl:1][c:2]1[cH:3][n:4][n:5]([CH3:16])[c:6]1-[c:7]1[cH:8][c:9]([C:13](=[O:15])[NH:17][CH:18]([CH2:19][N:20]2[C:21](=[O:30])[c:22]3[cH:23][cH:24][cH:25][cH:26][c:27]3[C:28]2=[O:29])[CH2:31][c:32]2[cH:33][c:34]([F:39])[c:35]([F:38])[cH:36][cH:37]2)[o:10][c:11]1[CH3:12]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-539081d07dee408d9123d8349ba19288
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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