m-Chloroperbenzoic acid → HCID 22052523, compound

HRID 1369922Notes

Reaction equation

HRID 1369922 reaction equation
[CH:1]([C:3]1[CH:4]=[CH:5][C:6]2[C:7]3[CH2:16][CH2:15][CH2:14][C:8]=3[C:9](=[O:13])[NH:10][C:11]=2[CH:12]=1)=[CH2:2].C1C=C(Cl)C=C(C(OO)=[O:25])C=1>C(Cl)(Cl)Cl>[O:25]1[CH2:2][CH:1]1[C:3]1[CH:4]=[CH:5][C:6]2[C:7]3[CH2:16][CH2:15][CH2:14][C:8]=3[C:9](=[O:13])[NH:10][C:11]=2[CH:12]=1

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 22052505HCID 22052505, compound

Product 1

HCID 22052523HCID 22052523, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

A solution of 1.41 g (6.7 mmol) of 7-vinyl-1,2,3,5-tetrahydrocyclopenta[c]-quinolin-4-one in 200 ml of chloroform is mixed at room temperature with mCPBA. After 15 hours at room temperature, the batch is washed with saturated Na2SO3 (2×100 ml), dried (Na2SO4) and concentrated by evaporation in a vacuum. Column chromatography on silica gel with hexane-ethyl acetate yields 0.59 g of product.

Workup

  1. washthe batch is washed with saturated Na2SO3 (2×100 ml)
  2. dry with materialdried (Na2SO4)
  3. concentrationconcentrated by evaporation in a vacuum

Sources & evidence

ORD record
ord-8440f240c6d041b483ca9f5cc6a123bd
Source dataset
uspto-grants-2003_06
Patent number
US06579883B1

Reaction notes

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