Potassium Cation → N-[5-(4-methylpiperazin-1-yl)-3,4-dihydro-2H-chromen-3-yl]-4-[4-(2-phenylmethoxyethyl)piperazin-1-yl]benzamide

HRID 137007Notes

Reaction equation

HRID 137007 reaction equation
[C:33](=[O:34])([O-:35])[O-:36].[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([c:8]2[cH:9][cH:10][cH:11][c:12]3[c:13]2[CH2:14][CH:15]([NH:18][C:19]([c:20]2[cH:21][cH:22][c:23]([N:26]4[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]4)[cH:24][cH:25]2)=[O:32])[CH2:16][O:17]3)[CH2:6][CH2:7]1.[CH3:39][S:40]([O:41][CH2:44][CH2:45][O:46][CH2:47][c:48]1[cH:49][cH:50][cH:51][cH:52][cH:53]1)(=[O:42])=[O:43].[CH3:54][N:55]([CH3:56])[CH:57]=[O:58].[K+:37].[K+:38]>>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([c:8]2[cH:9][cH:10][cH:11][c:12]3[c:13]2[CH2:14][CH:15]([NH:18][C:19]([c:20]2[cH:21][cH:22][c:23]([N:26]4[CH2:27][CH2:28][N:29]([CH2:44][CH2:45][O:46][CH2:47][c:48]5[cH:49][cH:50][cH:51][cH:52][cH:53]5)[CH2:30][CH2:31]4)[cH:24][cH:25]2)=[O:32])[CH2:16][O:17]3)[CH2:6][CH2:7]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 9824299N-[5-(4-Methylpiperazin-1-yl)-3,4 dihydro-2H-1-benzopyran-3-yl]-4-(piperazin-1-yl)benzamideHCID 108572722-Benzyloxyethyl mesylate

Product 1

HCID 22064026N-[5-(4-methylpiperazin-1-yl)-3,4-dihydro-2H-chromen-3-yl]-4-[4-(2-phenylmethoxyethyl)piperazin-1-yl]benzamide

Sources & evidence

ORD record
ord-5084fe7453314c48a6344a9e18cb102a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…