4-Aminophenol → HCID 18511552, compound

HRID 1370523Notes

Reaction equation

HRID 1370523 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.[Cl:9][C:10]1[CH:15]=[C:14]([C:16]([F:19])([F:18])[F:17])[CH:13]=[CH:12][C:11]=1[S:20](Cl)(=[O:22])=[O:21]>>[Cl:9][C:10]1[CH:15]=[C:14]([C:16]([F:18])([F:17])[F:19])[CH:13]=[CH:12][C:11]=1[S:20]([NH:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1)(=[O:22])=[O:21]

Participants

3

Reactant 2

HCID 4034-AminophenolHCID 27366752-Chloro-4-(trifluoromethyl)benzenesulfonyl chloride

Product 1

HCID 18511552HCID 18511552, compound

Procedure

2-Chloro-N-(4-hydroxy-phenyl)-4-trifluoromethyl-benzenesulfonamide was synthesized (98%) from 4-aminophenol (Aldrich) and 2-chloro-4-trifluoromethylbenzenesulfonyl chloride in a similar manner as described in Example 421.

Sources & evidence

ORD record
ord-59ddcca7688846e9bdad50f75f5e9a01
Source dataset
uspto-grants-2003_06
Patent number
US06583157B2

Reaction notes

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