HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl Isothiocyanate → HCID 18511664, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl Isothiocyanate | HCID 7673 | — |
| Reactant | 1-[4-(4-Fluorophenoxy)butyl]-4-methylaminopiperidine dihydrochloride | HCID 18511646 | — |
| Product | HCID 18511664 | HCID 18511664 | — |
Reaction Steps
The condensation of 2 g (14.8 mmol) of phenyl isothiocyanate with 5.25 g (14.8 mmol) of 1-[4-(4-fluorophenoxy)butyl]-4-methylaminopiperidine dihydrochloride (cf. WO 97/05134) according to the protocol of Example 1.1 provides 5.5 g (Yd: 90%) of white crystals of formula 7.1:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06583159B1 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-480dcf4e93fd4c948256b2ee20c5be4d |
| Source note | uspto-grants-2003_06 |