HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3-Bis(4-methoxyphenyl)-propanaldehyde → 2-Cyclohexyl-6-{4-[3,3-bis(4-methoxyphenyl)-1-propyl]-piperazin-1-yl}-2,3-dihydro-1H-isoindol-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3-Bis(4-methoxyphenyl)-propanaldehyde | HCID 13299492 | — |
| Reactant | HCID 22180413 | HCID 22180413 | — |
| Product | 2-Cyclohexyl-6-{4-[3,3-bis(4-methoxyphenyl)-1-propyl]-piperazin-1-yl}-2,3-dihydro-1H-isoindol-1-one | HCID 18510924 | 59.8% |
Reaction Steps
In the same manner as in Example 38, the title compound (52 mg) was prepared from the compound (47 mg) obtained in step (e) of Example 1 and the compound (110 mg) obtained in step (b).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06583144B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-e7a924eea7e446dc890bdc3590937677 |
| Source note | uspto-grants-2003_06 |