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Bromocycloheptane → 2-Cycloheptyl-6-[4-(3,3-diphenyl-1-propyl)-piperazin-1-yl]-2,3-dihydro-1H-isoindol-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Bromocycloheptane | HCID 16992 | — |
| 反応物 | 2,3-Dihydro-6-[4-(3,3-diphenyl-1-propyl)piperazin-1-yl]-1H-isoindol-1-one | HCID 18510931 | — |
| 生成物 | 2-Cycloheptyl-6-[4-(3,3-diphenyl-1-propyl)-piperazin-1-yl]-2,3-dihydro-1H-isoindol-1-one | HCID 18510940 | 19.5% |
反応手順
In the same manner as in Example 51, the title compound (12 mg) was prepared from the compound (50 mg) obtained in Example 50 and cycloheptyl bromide (32 mg).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06583144B2 |
| 出典データセット | uspto-grants-2003_06 |
| ORD ID | ord-aba4e8f4dfb240a48b2c666620b48196 |
| 出典メモ | uspto-grants-2003_06 |