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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1370573Generated: October 26, 2026

1,2,3-Trimethoxybenzene → 2,3,4-trimethoxybenzenesulfonyl Chloride

https://huagongshe.com/reaction/1370573

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2,3-TrimethoxybenzeneHCID 12462—
ReactantChlorosulfonic acidHCID 24638—
SolventChloroformHCID 6212—
Product2,3,4-trimethoxybenzenesulfonyl ChlorideHCID 4712742—

Reaction Steps

2,3,4-Trimethoxybenzenesulfonyl chloride is synthesized by reaction of pyrogallol trimethyl ether with chlorosulfonic acid in chloroform at 0° C. according to the procedure described in G. Pifferi and R. Monguzzi, Journal of Pharmaceutical Sciences, 1973, 62, 1393.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06583161B1
Source datasetuspto-grants-2003_06
ORD IDord-fb0d33638d034a34a47f07c3fa4693de
Source noteuspto-grants-2003_06