反应详情

A solution of 29 g of 3,4-diethoxybenzonitrile and 23 g of thioacetamide in 120 ml of 10% hydrochloric acid-DMF was stirred at 90° C. for 3 hours and then 130° C. for 5 hours. After evaporation of the solvent, the residue was washed with diethyl ether (2×100 ml) and water (2×100 ml). The resulting crystals were collected by filtration and dried to obtain 21.7 g of 3,4-diethoxythiobenzamide.

1. customAfter evaporation of the solvent
2. washthe residue was washed with diethyl ether (2×100 ml) and water (2×100 ml)
3. filtrationThe resulting crystals were collected by filtration
4. customdried