3-Hydroxypiperidine → HCID 18752892, compound

HRID 1370586Notes

Reaction equation

HRID 1370586 reaction equation
[NH2:1][C:2]1[C:7](/[CH:8]=[CH:9]/[C:10]([OH:12])=O)=[CH:6][C:5]([Cl:13])=[CH:4][N:3]=1.[OH:14][CH:15]1[CH2:20][CH2:19][CH2:18][NH:17][CH2:16]1>>[NH2:1][C:2]1[C:7](/[CH:8]=[CH:9]/[C:10]([N:17]2[CH2:18][CH2:19][CH2:20][CH:15]([OH:14])[CH2:16]2)=[O:12])=[CH:6][C:5]([Cl:13])=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 232933-HydroxypiperidineHCID 18752895HCID 18752895, compound

Product 1

HCID 18752892HCID 18752892, compound

Procedure

The title compound was prepared from (E)-3-(2-amino-5-chloro-3-pyridinyl)-2-propenoic acid and 3-hydroxypiperidine as a white solid:

Sources & evidence

ORD record
ord-5ca1e293b61c4644907fb254b63200e5
Source dataset
uspto-grants-2003_06
Patent number
US06583162B1

Reaction notes

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