Vinylcyclohexane → HCID 18752902, compound

HRID 1370590Notes

Reaction equation

HRID 1370590 reaction equation
Br[C:2]1[C:3]([NH2:9])=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1.[CH:10]([CH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)=[CH2:11]>CCCCCC>[Cl:8][C:6]1[CH:7]=[C:2](/[CH:11]=[CH:10]/[CH:12]2[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]2)[C:3]([NH2:9])=[N:4][CH:5]=1

Participants

4

Reactant 2

HCID 12757VinylcyclohexaneHCID 27639713-Bromo-5-chloropyridin-2-amine

Product 1

HCID 18752902HCID 18752902, compound

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

The title compound was prepared from 3-bromo-5-chloro-2-pyridinamine and vinylcyclohexane. Purification by column chromatography on silica gel eluting with hexane—EtOAc (80:20) gave a pale yellow oil. An analytical sample was prepared by crystallisation from hexane:

Workup

  1. customPurification by column chromatography on silica gel eluting with hexane—EtOAc (80:20)
  2. customgave a pale yellow oil

Sources & evidence

ORD record
ord-3342317b5d904046902f334d7245b3d8
Source dataset
uspto-grants-2003_06
Patent number
US06583162B1

Reaction notes

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