反应详情

The product from Example 306B in ethanol (1.2 mL) and H2O (0.6 mL) was treated with iron powder (100 mg, 1.8 mmoles) and NH4Cl (10 mg, 0.18 mmoles) at 80° C. overnight. The reaction mixture filtered, residue washed with methanol and dichloromethane, the filtrate concentrated in vacuo to provide the title compound.

1. filtrationThe reaction mixture filtered
2. washresidue washed with methanol and dichloromethane
3. concentrationthe filtrate concentrated in vacuo