HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonyl chloride → HCID 86586240, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | Ethyl (5-(4-(((3-amino-2-methylphenyl)(2-fluorobenzyl)amino)methyl)phenoxy)-2-chlorophenoxy)acetate | HCID 86586238 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 86586240 | HCID 86586240 | — |
Reaction Steps
The product from Example 306C in anhydrous pyridine (1.5 mL) was cooled at 0° C. and treated with methane sulfonyl chloride (0.042 mL, 0.54 mmoles) at 0° C. for 1 hour, then room temperature for 1 hour. The reaction mixture concentrated in vacuo, residue dissolved in dichloromethane, filtered and filtrate concentrated in vacuo to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06583180B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-2a45ec5b3a6648439ececd5297c975d9 |
| Source note | uspto-grants-2003_06 |