HCID 18510226, compound → HCID 18510251, compound

HRID 1371042Notes

Reaction equation

HRID 1371042 reaction equation
[C:1]1([C:7](=[O:24])[CH:8]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH2:9]/[CH:10]=[CH:11]/[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>CCOC(C)=O.[Pd]>[C:1]1([C:7](=[O:24])[CH:8]([C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH2:9][CH2:10][CH2:11][C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 1

HCID 18510226HCID 18510226, compound

Product 1

HCID 18510251HCID 18510251, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

To the compound of Example 9 Step 1 (0.20 g, 0.64 mmole) dissolved in EtOAc was added Pd/C. The reaction was then stirred for 2 h under 1 atmosphere of H2, and was then filtered through celite and evaporated.

Workup

  1. filtrationwas then filtered through celite
  2. customevaporated

Sources & evidence

ORD record
ord-c9a6baf79ff14fa4afae39072141c991
Source dataset
uspto-grants-2003_06
Patent number
US06583126B2

Reaction notes

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