HCID 88102920, compound → HCID 88104079, compound

HRID 1371043Notes

Reaction equation

HRID 1371043 reaction equation
[C:1]([C:9]([C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)([CH2:24]/[CH:25]=[CH:26]/[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)[CH2:10][C:11]1[CH:16]=[CH:15][C:14]([O:17][P:18]([CH:21]([F:23])[F:22])(=[O:20])[OH:19])=[CH:13][CH:12]=1)(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CCOC(C)=O.[Pd]>[CH2:1]([C:9]([C:33]1[CH:34]=[CH:35][CH:36]=[CH:37][CH:38]=1)([CH2:24][CH2:25][CH2:26][C:27]1[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=1)[CH2:10][C:11]1[CH:16]=[CH:15][C:14]([O:17][P:18]([CH:21]([F:22])[F:23])(=[O:19])[OH:20])=[CH:13][CH:12]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 1

HCID 88102920HCID 88102920, compound

Product 1

HCID 88104079HCID 88104079, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

The compound of Example 9 in EtOAc was treated with Pd/C and H2 (50 psi) for 2 days. After filtration and evaporation the title compound was obtained.

Workup

  1. filtrationAfter filtration and evaporation the title compound
  2. customwas obtained

Sources & evidence

ORD record
ord-46514555590d470bb0b66ceb49cf2736
Source dataset
uspto-grants-2003_06
Patent number
US06583126B2

Reaction notes

Loading…