1-Acetylpiperazine → HCID 21070187, compound

Participants

Reaction Steps

Prepared from the reaction of 2-chloro-N-(5-oxo-5,9-dihydro-4H-cyclopenta[lmn]phenanthridin-1-yl)-acetamide 8 and 1-piperazin-1-yl-ethanone (0.1 mL) according to General Procedure B. White solid in 58% yield, mp155–157° C. 1H-NMR (300 MHz, DMSO-d6) □ 11.44(s, 1H); 9.85(s, 1H); 7.93(d, 2H); 7.61(m, 2H); 7.13(d, 1H, J=8.2 Hz); 4.25(s, 2H); 3.56(s, 4H); 3.24(s, 2H); 2.57(s, 2H); 2.54(s, 2H); 2.02(s, 3H). Anal (C22H22N2O3 1.3 H2O) C H N.

Provenance & Evidence