Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1371388Generated: November 2, 2026

tert-butyl 4-({[({[(2S)-4-(3,4-dichlorobenzyl)morpholin-2-yl]methyl}amino)carbonyl]amino}methyl)piperidine-1-carboxylate → HCID 69507286, compound

https://huagongshe.com/reaction/1371388

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl 4-({[({[(2S)-4-(3,4-dichlorobenzyl)morpholin-2-yl]methyl}amino)carbonyl]amino}methyl)piperidine-1-carboxylateHCID 69507185—
SolventHydrochloric AcidHCID 313—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 69507286HCID 69507286268%

Reaction Steps

Intermediate 17 (0.390 g) was stirred in 4.0M hydrogen chloride in dioxane (4 ml) for 2 h, at 23° C. under nitrogen. The solvent was removed in vacuo, azeotroped with dichloromethane (20 ml), and dried under vacuum to give the title compound as a pale yellow solid, (0.33 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07157457B2
Source datasetuspto-grants-2007_01
ORD IDord-831c3995610342df8a7810b329294ee9
Source noteuspto-grants-2007_01