Homoallyl bromide → HCID 9923257, compound

HRID 1371426Notes

Reaction equation

HRID 1371426 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([NH:11][CH2:12][CH:13]2[O:18][CH2:17][CH2:16][NH:15][CH2:14]2)=[O:10])=[CH:4][CH:3]=1.Br[CH2:20][CH2:21][CH:22]=[CH2:23]>>[CH2:23]([N:15]1[CH2:16][CH2:17][O:18][CH:13]([CH2:12][NH:11][C:9]([NH:8][C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=2)=[O:10])[CH2:14]1)[CH2:22][CH:21]=[CH2:20]

Participants

3

Reactant 2

HCID 21241Homoallyl bromideHCID 23089254N-(4-Chlorophenyl)-N'-(morpholin-2-ylmethyl)urea

Product 1

HCID 9923257HCID 9923257, compound

Procedure

Example 27 was prepared in an analogous manner to Example 19 using a mixture of Intermediate 9 (0.01 g) and 4-bromobut-1-ene (4.1 μl) to give the title compound (0.0027 g).

Workup

  1. customExample 27 was prepared in an analogous manner to Example 19 using

Sources & evidence

ORD record
ord-c197a61ce23340d8805dafc4ee204455
Source dataset
uspto-grants-2007_01
Patent number
US07157457B2

Reaction notes

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