HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Dimethylamino)phenyl isocyanate → N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-N'-[4-(dimethylamino)phenyl]urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Dimethylamino)phenyl isocyanate | HCID 2733372 | — |
| Reactant | [4-(3,4-Dichlorobenzyl)morpholin-2-yl]methylamine | HCID 10308229 | — |
| Product | N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-N'-[4-(dimethylamino)phenyl]urea | HCID 10181536 | 78% |
Reaction Steps
Example 36 was prepared in an analogous manner to Example 1 using a mixture of Intermediate 3 (0.025 g) and 4-isocyanato-N,N-dimethylaniline (0.0221 g) to give the title compound (0.031 g). LC-MS (System A): Rt 1.68 mins, Mass Spectrum m/z 437 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157457B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-639f57edf2724baeb93a06bc83371863 |
| Source note | uspto-grants-2007_01 |