HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-(chloromethyl)thiophene → N-(4-Chlorophenyl)-N'-({4-[(5-chlorothien-2-yl)methyl]morpholin-2-yl}methyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-(chloromethyl)thiophene | HCID 583079 | — |
| Reactant | N-(4-Chlorophenyl)-N'-(morpholin-2-ylmethyl)urea | HCID 23089254 | — |
| Product | N-(4-Chlorophenyl)-N'-({4-[(5-chlorothien-2-yl)methyl]morpholin-2-yl}methyl)urea | HCID 10272295 | 66% |
Reaction Steps
Example 37 was prepared in an analogous manner to Example 19 using a mixture of Intermediate 9 (0.01 g) and 2-chloro-5-(chloromethyl)thiophene (0.0068 g) to give the title compound (0.0098 g). LC-MS (System A): Rt 2.84 mins, Mass Spectrum m/z 400 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157457B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-90864ac9f6f846b58ee8c5dec4529ca8 |
| Source note | uspto-grants-2007_01 |