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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1371511Generated: November 2, 2026

Piperazine → 8-(Piperazin-1-yl)isoquinoline

https://huagongshe.com/reaction/1371511

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazineHCID 4837—
Reactant8-BromoisoquinolineHCID 9859134—
Product8-(Piperazin-1-yl)isoquinolineHCID 21070960—

Reaction Steps

8-(Piperazin-1-yl)isoquinoline is prepared from 8-bromoisoquinoline and piperazine using the coupling procedure as described in Step 1 of Preparation 54A to afford about 270 mg (88%). EIS-MS 214.0 M+1

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07157463B2
Source datasetuspto-grants-2007_01
ORD IDord-15d1ac9c904e4d9db88ce2ad6cc92969
Source noteuspto-grants-2007_01