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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1371513Generated: October 28, 2026

Piperazine → 8-(1-piperazinyl)Quinoline

https://huagongshe.com/reaction/1371513

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazineHCID 4837—
Reactant8-BromoquinolineHCID 140109—
Product8-(1-piperazinyl)QuinolineHCID 11830786—

Reaction Steps

8-(Piperazin-1-yl)quinoline is prepared from 8-bromoquinoline and piperazine as described in Step 1 of Preparation 54A to afford about 490 mg (95%). EIS-MS 207.8 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07157463B2
Source datasetuspto-grants-2007_01
ORD IDord-6a9a3eb341b84319b70a186d86bdea3d
Source noteuspto-grants-2007_01