HRID1371552

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21071295

未命名化合物

HCID21071303

未命名化合物

PRODUCTS

产物

HCID21071306

未命名化合物

PROCEDURE

实验过程

Prepared from 3-(3-(N-Boc-piperidin-4-yl)-propoxy)-phenylacetic acid and N-(4-(5-amino-1,3,4-thiadiazol-2-yl)-1,2,5-oxadiazol-3-yl)-2,2,2-trifluoroacetamide by methods substantially similar to those described in Example 11, supra. Yield 30 mg.

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-1e1e480e91dd46bca4ad85975386981c
来源数据集: uspto-grants-2007_01
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US07157476B2
来源说明: uspto-grants-2007_01

反应SMILES

[C:1]([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][CH2:15][CH2:16][O:17][C:18]2[CH:19]=[C:20]([CH2:24][C:25](O)=[O:26])[CH:21]=[CH:22][CH:23]=2)[CH2:10][CH2:9]1)([O:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:2].[NH2:28][C:29]1[S:33][C:32]([C:34]2[C:35]([NH:39][C:40](=[O:45])[C:41]([F:44])([F:43])[F:42])=[N:36][O:37][N:38]=2)=[N:31][N:30]=1>>[F:43][C:41]([F:42])([F:44])[C:40]([NH:39][C:35]1[C:34]([C:32]2[S:33][C:29]([NH:28][C:25](=[O:26])[CH2:24][C:20]3[CH:21]=[CH:22][CH:23]=[C:18]([O:17][CH2:16][CH2:15][CH2:14][CH:11]4[CH2:10][CH2:9][N:8]([C:1]([O:3][C:4]([CH3:7])([CH3:5])[CH3:6])=[O:2])[CH2:13][CH2:12]4)[CH:19]=3)=[N:30][N:31]=2)=[N:38][O:37][N:36]=1)=[O:45]