HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(3-(N-Boc-piperidin-4-yl)-propoxy)-phenylacetic acid → N-Trifluoroacetyl-4-(5-(3-(3-(N-Boc-piperidin-4-yl)-propoxy)-phenylacetyl)amino-[1,3,4]thiadiazol-2-yl)-furazan-3-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(3-(N-Boc-piperidin-4-yl)-propoxy)-phenylacetic acid | HCID 21071295 | — |
| Reactant | N-(4-(5-amino-1,3,4-thiadiazol-2-yl)-1,2,5-oxadiazol-3-yl)-2,2,2-trifluoroacetamide | HCID 21071303 | — |
| Product | N-Trifluoroacetyl-4-(5-(3-(3-(N-Boc-piperidin-4-yl)-propoxy)-phenylacetyl)amino-[1,3,4]thiadiazol-2-yl)-furazan-3-ylamine | HCID 21071306 | — |
Reaction Steps
Prepared from 3-(3-(N-Boc-piperidin-4-yl)-propoxy)-phenylacetic acid and N-(4-(5-amino-1,3,4-thiadiazol-2-yl)-1,2,5-oxadiazol-3-yl)-2,2,2-trifluoroacetamide by methods substantially similar to those described in Example 11, supra. Yield 30 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157476B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-1e1e480e91dd46bca4ad85975386981c |
| Source note | uspto-grants-2007_01 |