HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → HCID 11974834, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | 2-Iodophenol | HCID 10784 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-Pyrimidinecarboxamide, 4-amino-2-(ethylthio)-N-methoxy-N-methyl- | HCID 11974832 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 11974834 | HCID 11974834 | — |
Reaction Steps
The product of the reaction of 2-iodophenol (Aldrich) and ethyl iodide in hot acetone containing potassium carbonate was treated with n-butyl lithium as described in Example 2A and subsequently reacted with 4-amino-2-ethylsulfanyl-pyrimidine-5-carboxylic acid methoxy-methyl-amide, Example 1, using the procedure of Example 47 to give (4-amino-2-ethylsulfanyl-pyrimidin-5-yl)-(2-ethoxy-phenyl)-methanone as a white solid. MS (M+H)+, 304
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157455B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-4b11e9cae7c540cbb589b386e2557592 |
| Source note | uspto-grants-2007_01 |