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HRID1371660

反应详情

EQUATION

反应方程式

HRID 1371660 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)c1sccc1S(=O)(=O)Cl
HCID2736733

2-Thiophenecarboxylic acid, 3-(chlorosulfonyl)-, methyl ester

C6H5ClO4S2

结构：COc1ccc(F)cc1C(=O)c1cnc(NC2CCNCC2)nc1N
HCID9997668

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1sccc1S(=O)(=O)N1CCC(Nc2ncc(C(=O)c3cc(F)ccc3OC)c(N)n2)CC1
HCID58777631

未命名化合物

PROCEDURE

实验过程

This compound was prepared from [4-amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone, Example 59, and 2-carbomethoxy-3-thiophenesulfonyl chloride (Maybridge) by the procedure described in Example 152. HR-MS (ES, m/z) calculated for C23H25FN5O6S2 [(M+H)+] 550.1225, observed 550.1232.