HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 86760350, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | L-Tartaric acid | HCID 444305 | — |
| Reactant | HCID 21071662 | HCID 21071662 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86760350 | HCID 86760350 | — |
Reaction Steps
Add L-(+)-tartaric acid (49 mg, 0.33 mmol) and methanol to a solution of (N-(2-(7-fluoro-1H-indol-3-yl)ethyl)-3-(2,2,3,3-tetrafluoropropoxy)benzylamine (130 mg, 0.33 mmol) in ethyl acetate. Evaporate the solvent to give a gum. Crystallize the gum from diethyl ether/ethyl acetate to give the title compound: mp 192–194° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157488B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-c61c4bf8248b4f569b7ff9e42ab90310 |
| Source note | uspto-grants-2007_01 |