HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1372006Generated: October 30, 2026
Dimethylformamide → HCID 178434610, compound
https://huagongshe.com/reaction/1372006
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | 1H-Pyrazole, 3-methyl-5-(trifluoromethyl)- | HCID 139077 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178434610 | HCID 178434610 | — |
Reaction Steps
3-methyl-5-trifluoromethylpyrazole was taken into dry DMF (20 mL) and N-chloro succinimide (1.78 g) was added in portions. The mixture was then heated at 70° C. for 22 h, cooled to room temperature, and then water (100 mL) was added and the mixture extracted with ethyl acetate (4×25 mL). The organic layer was washed with water and brine and dried with Na2SO4. Evaporation of the solvent afforded the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07157464B2 |
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| Source dataset | uspto-grants-2007_01 |
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| ORD ID | ord-c19a261cb19544f488f88069e19c818b |
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| Source note | uspto-grants-2007_01 |
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