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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 137212Generated: October 26, 2026

1-[(5-Bromo-2-thienyl)sulfonyl]-4-methylpiperazine → 5-(4-Chloro-3-methyl-phenyl)-7-difluoromethyl-3-[5-(4-methyl-piperazine-1-sulfonyl)-thiophen-2-ylethynyl]-pyrazolo[1,5-a]pyrimidine

https://huagongshe.com/reaction/137212

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[(5-Bromo-2-thienyl)sulfonyl]-4-methylpiperazineHCID 662157—
Reactant5-(4-Chloro-3-methyl-phenyl)-7-difluoromethyl-3-ethynyl-pyrazolo[1,5-a]pyrimidineHCID 86608084—
Product5-(4-Chloro-3-methyl-phenyl)-7-difluoromethyl-3-[5-(4-methyl-piperazine-1-sulfonyl)-thiophen-2-ylethynyl]-pyrazolo[1,5-a]pyrimidineHCID 67001039—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-dfe07de3566e4457ae1fee38b0fe6730
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)