huagongshe.com
HRID1372406

反应详情

EQUATION

反应方程式

HRID 1372406 的结构方程式

REACTANTS

反应物

3
结构：O
HCID962

Water

H2O

结构：[K+].[OH-]
HCID14797

Potassium hydroxide

HKO

结构：CCOC(=O)c1cc(C=O)c[nH]1
HCID321486

ethyl 4-formyl-1H-pyrrole-2-carboxylate

C8H9NO3

PRODUCTS

生成物

1
结构：O=Cc1c[nH]c(C(=O)O)c1
HCID13780813

4-Formyl-1H-pyrrole-2-carboxylic acid

C6H5NO3

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Refluxing 4-formyl-1H-pyrrole-2-carboxylic acid ethyl ester in 2 equivalents of potassium hydroxide in methanol:water followed by acidification to pH 3 at 0° C. gave 4-formyl-1H-pyrrole-2-carboxylic acid as a solid. MS m/z 140 [M+1].

WORKUP

后处理

  1. customfollowed by acidification to pH 3 at 0° C.