HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 4-Formyl-1H-pyrrole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Ethyl 4-formyl-1H-pyrrole-2-carboxylate | HCID 321486 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-Formyl-1H-pyrrole-2-carboxylic acid | HCID 13780813 | — |
Reaction Steps
Refluxing 4-formyl-1H-pyrrole-2-carboxylic acid ethyl ester in 2 equivalents of potassium hydroxide in methanol:water followed by acidification to pH 3 at 0° C. gave 4-formyl-1H-pyrrole-2-carboxylic acid as a solid. MS m/z 140 [M+1].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157577B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-ed685f93b0ad464a8e4d4930aabc27c0 |
| Source note | uspto-grants-2007_01 |