Hydrochloric Acid → 690258-15-2

HRID 1372477Notes

Reaction equation

HRID 1372477 reaction equation
[ClH:1].[I:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[C:6]#[N:7].[CH2:11]([OH:13])[CH3:12]>>[ClH:1].[I:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[C:6](=[NH:7])[O:13][CH2:11][CH3:12]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 1443413-Iodobenzonitrile

Product 1

HCID 21071767690258-15-2

Procedure

Hydrogen chloride gas was bubbled into a solution of 3-iodobenzonitrile (2.00 g, 8.73 mmol) in 20 mL of absolute ethanol for 30 min at room temperature. The resultant solution was kept at room temperature for 48 h, and was then concentrated under reduced pressure. The residue was triturated with diethyl ether, collected and dried in vacuo to afford the product as a white powder.

Workup

  1. concentrationwas then concentrated under reduced pressure
  2. customThe residue was triturated with diethyl ether
  3. customcollected
  4. customdried in vacuo

Sources & evidence

ORD record
ord-c7103b4c208e44de95d4a2f34789ed17
Source dataset
uspto-grants-2007_01
Patent number
US07157490B2

Reaction notes

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