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HRID1372942

反应详情

EQUATION

反应方程式

HRID 1372942 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C(=O)O)C(=O)NCC(F)(F)C(F)(F)F
HCID21072482

未命名化合物

结构：N[C@@H]1C(=O)Nc2ccccc2-c2ccccc21
HCID25067537

(7S)-7-Amino-5,7-dihydro-6H-dibenzo[b,d]azepin-6-one

C14H12N2O

PRODUCTS

生成物

1
结构：CC(C)(C(=O)NCC(F)(F)C(F)(F)F)C(=O)N[C@@H]1C(=O)Nc2ccccc2-c2ccccc21
HCID49867930

N-((7S)-6,7-Dihydro-6-oxo-5H-dibenz(b,d)azepin-7-yl)-2,2-dimethyl-N'-(2,2,3,3,3-pentafluoropropyl)-propanediamide

C22H20F5N3O3

PROCEDURE

实验过程

(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one was coupled with 2,2-dimethyl-N-(2,2,3,3,3-pentafluoro-propyl)-malonamic acid in analogy to the description in examples 65 and 66 to yield 2,2-dimethyl-N-((S)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N′-(2,2,3,3,3-pentafluoro-propyl)-malonamide,