HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propanoic acid, 2,2-dimethyl-3-oxo-3-[(2,2,3,3,3-pentafluoropropyl)amino]- → Ro 4929097
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propanoic acid, 2,2-dimethyl-3-oxo-3-[(2,2,3,3,3-pentafluoropropyl)amino]- | HCID 21072482 | — |
| Reactant | (7S)-7-Amino-5,7-dihydro-6H-dibenzo[b,d]azepin-6-one | HCID 25067537 | — |
| Product | Ro 4929097 | HCID 49867930 | — |
Reaction Steps
(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one was coupled with 2,2-dimethyl-N-(2,2,3,3,3-pentafluoro-propyl)-malonamic acid in analogy to the description in examples 65 and 66 to yield 2,2-dimethyl-N-((S)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N′-(2,2,3,3,3-pentafluoro-propyl)-malonamide,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07160875B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-e21d355747ea4c35a157890ef9aa1c5e |
| Source note | uspto-grants-2007_01 |