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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1372954Generated: November 3, 2026

2-Methyl-malonic acid monoethyl ester → 2-methyl-N-(3,3,4,4,4-pentafluoro-butyl)-malonamic acid ethyl ester

https://huagongshe.com/reaction/1372954

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-malonic acid monoethyl esterHCID 295972—
Reactant3,3,4,4,4-Pentafluorobutan-1-amineHCID 15754740—
Product2-methyl-N-(3,3,4,4,4-pentafluoro-butyl)-malonamic acid ethyl esterHCID 86596825—

Reaction Steps

2-Methyl-malonic acid monoethyl ester was coupled with 3,3,4,4,4-pentafluoro-butylamine in analogy to the description in example 73 to yield 2-methyl-N-(3,3,4,4,4-pentafluoro-butyl)-malonamic acid ethyl ester as colourless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07160875B2
Source datasetuspto-grants-2007_01
ORD IDord-da2763d5f4dc41828473a75d9f12bdbf
Source noteuspto-grants-2007_01