2-Methyl-N-(2,2,3,3,3-pentafluoro-propyl)-malonamic acid → HCID 86760355, compound

Participants

Reaction Steps

In an analogous manner to that described in Example 20 d) and 27, the condensation of (S)-5-acetyl-3-amino-1-benzyl-1,3,4,5-tetrahydro-benzo[b][1,4]diazepin-2-one and (2RS)-methyl-N-(2,2,3,3,3-pentafluoro-propyl)-malonamic acid [see Example 25 b)] yielded the title compound as a white solid; MS: m/e=539 (M−H)−.

Provenance & Evidence