HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3,3-Trifluoropropylamine → (R)-2-Fluoro-2-methyl-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N'-(3,3,3-trifluoro-propyl)-malonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3,3-Trifluoropropylamine | HCID 10001 | — |
| Reactant | HCID 69040656 | HCID 69040656 | — |
| Product | (R)-2-Fluoro-2-methyl-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N'-(3,3,3-trifluoro-propyl)-malonamide | HCID 69043342 | — |
Reaction Steps
The title compound [MS m/e (%): 452.3 (M+H+, 100)]was prepared in analogy to example 14 from 3,3,3-trifluoropropylamine and (2S)-2-fluoro-2-methyl-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-malonamic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07160875B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-642ab95245ad43dcab8bdb8610cf7689 |
| Source note | uspto-grants-2007_01 |