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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1373027Generated: October 25, 2026

2-Dimethylaminopyridine → HCID 178469736, compound

https://huagongshe.com/reaction/1373027

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-DimethylaminopyridineHCID 21885—
ReactantEthyl 4-chloro-2-phenylpyrimidine-5-carboxylateHCID 239537—
ReactantHCID 178419079HCID 178419079—
SolventEthanolHCID 702—
ProductHCID 178469736HCID 178469736—

Reaction Steps

Ethyl 4-chloro-2-phenyl-5-pyrimidinecarboxylate and N-tert-butoxycarbonyl-trans-1,4-cyclohexanediamine were reacted in ethanol in the presence of dimethylaminopyridine in the same manner as in Reference Example 3-49 to obtain N-tert-butoxycarbonyl-trans-4-(5-ethoxycarbonyl-2-phenyl-4-pyrimidinylamino)cyclohexylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07160877B2
Source datasetuspto-grants-2007_01
ORD IDord-7cdd0e493b5a4360ae82acfd3eef692d
Source noteuspto-grants-2007_01