反应详情

20.0 g (105 mmol) of 1-acetyl-5-amino-2-indolinone are placed in 200 ml of pyridine, combined with 15.3 ml (120 mmol) of benzenesulphonic acid chloride while cooling with ice and stirred for 2 hours. Then the mixture is poured onto 1.8 l of water and suction filtered. The crude product is stirred into acetone, suction filtered and dried.

1. temperaturewhile cooling with ice
2. filtrationfiltered
3. stirringThe crude product is stirred into acetone, suction
4. filtrationfiltered
5. customdried