HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 178483746, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | (Z)-1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-5-(N-methyl-N-phenylsulphonyl-amino)-2-indolinone | HCID 18005732 | — |
| Reactant | 4-[N-(2-dimethylamino-ethyl)-N-methylsulphonyl-amino]-aniline | HCID 22569663 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178483746 | HCID 178483746 | — |
Reaction Steps
Prepared analogously to Example 1f from 350 mg (0.73 mmol) of (Z)-1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-5-(N-methyl-N-phenylsulphonyl-amino)-2-indolinone and 257 mg (1 mmol) of 4-[N-(2-dimethylamino-ethyl)-N-methylsulphonyl-amino]-aniline in DMF and subsequent treatment with sodium hydroxide solution.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07160901B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-67bd305621074c63895cc79d08de0b36 |
| Source note | uspto-grants-2007_01 |