HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 12789607, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Fluoro-2-nitrobenzene | HCID 73895 | — |
| Reactant | Benzeneacetic acid, 4-hydroxy-, methyl ester | HCID 518900 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 12789607 | HCID 12789607 | 96.9% |
Reaction Conditions
| Temperature | 140 °C |
|---|
Reaction Steps
A mixture of 2-fluoronitrobenzene (1.1 g, 10 mmols), methyl p-hydroxyphenylacetate (1.7 g, 10 mmols) and potassium carbonate (1.4 g, 10 mmols) was stirred at 140° C. for 1 hour. The reaction mixture was diluted with ethyl acetate, then washed with water, and thereafter dried with anhydrous magnesium sulfate. This was concentrated under reduced pressure to give an oil of methyl 4-(2-nitrophenoxy)phenylacetate (2.78 g, 96.9%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07160887B1 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-eb0770fc6e1d4489ae89372be529db71 |
| Source note | uspto-grants-2007_01 |