2-(Methylamino)ethanol → HCID 58781418, compound

HRID 1373390Notes

Reaction equation

HRID 1373390 reaction equation
Cl[C:2]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][N:9]=2)[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=2)[CH:3]=1.[CH3:20][NH:21][CH2:22][CH2:23][OH:24]>>[OH:24][CH2:23][CH2:22][N:21]([CH3:20])[C:2]1[CH:7]=[C:6]([C:8]2[CH:13]=[C:12]([N:21]([CH2:22][CH2:23][OH:24])[CH3:20])[CH:11]=[CH:10][N:9]=2)[N:5]=[C:4]([C:14]2[CH:19]=[C:18]([N:21]([CH3:20])[CH2:22][CH2:23][OH:24])[CH:17]=[CH:16][N:15]=2)[CH:3]=1

Participants

3

Reactant 2

HCID 80162-(Methylamino)ethanolHCID 6677484'-Chloro-2,2':6',2''-terpyridine

Product 1

HCID 58781418HCID 58781418, compound

Procedure

This compound is prepared in a manner analogous to that described in Example 7 with 4′-chloro-[2,2′;6′,2″]terpyridine, but instead the trichloro-substituted terpyridine L22 from Example 28, and 2-methylaminoethanol as amine component are used. 2-({4′,4″-Bis[(2-hydroxy-ethyl)-methyl-amino]-[2,2′;6′,2′]terpyridin-4-yl}methyl-amino)-ethanol, white solid. 13 C-NMR (90 MHz, DMSO-d6): 156.4 (quart.); 155.7 (quart.); 155.3 (quart.); 154.4 (quart.); 149.2 (tert.); 106.7 (tert.); 103.4 (tert.); 103.1 (tert.); 58.4 (2 signals, sec.); 58.2 (sec.); 53.6 (sec.); 53.5 (2 signals, sec.); 38.6 (prim.); 38.3 (2 signals, prim.).

Workup

  1. customThis compound is prepared in a manner analogous to

Sources & evidence

ORD record
ord-b9c51c8da1d54d37acb3bbd89f984cbd
Source dataset
uspto-grants-2007_01
Patent number
US07161005B2

Reaction notes

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